With technology, anything is possible even meeting a 2D anime character. In the following youtube video, a Japanese otaku has used some augmented reality technology and so able to interact with K-ON!!’s Azu-nyan.
However, this might be creepy to some. AND, WTF is that otaku doing??!!?! *RAGE* Anyway, I think most people might want to do that if they are given the chance. :3c